Chinese herbal formulas alleviated depression in breast cancer patients: A meta-analysis, network pharmacology and experimental validation

doi:10.5498/wjp.v16.i4.115981

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Apr 19, 2026; 16(4): 115981
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115981

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Figure 7 Chinese herbal formulas alleviated depression in breast cancer patients. RCTs: Randomized controlled trials; MD: Mean difference; IL: Interleukin; 5-HTP: 5-hydroxytryptophan; IAM: Indole-3-acetaldoxime; IAA: Indole-3-acetic acid; 5-HIAA: 5-hydroxyindoleacetic acid; CSCs: Cancer stem cells; GRP78: 78 kDa glucose regulated protein; LRP5: Lipoprotein receptor-related protein 5; LDHA: Lactate dehydrogenase A; PDK1: Pyruvate dehydrogenase kinase 1; PDHA: Pyruvate dehydrogenase alpha 1.

Citation: Hong SC, Du YY, Wang GB, Wang SQ, Zheng YF, Wang N, Situ HL, Wang ZY. Chinese herbal formulas alleviated depression in breast cancer patients: A meta-analysis, network pharmacology and experimental validation. World J Psychiatry 2026; 16(4): 115981
URL: https://www.wjgnet.com/2220-3206/full/v16/i4/115981.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i4.115981

Hong SC, Du YY, Wang GB, Wang SQ, Zheng YF, Wang N, Situ HL, Wang ZY. Chinese herbal formulas alleviated depression in breast cancer patients: A meta-analysis, network pharmacology and experimental validation. World J Psychiatry 2026; 16(4): 115981 [DOI: 10.5498/wjp.v16.i4.115981]

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