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Retrospective Study
Copyright: ©Author(s) 2026.
World J Psychiatry. Apr 19, 2026; 16(4): 115520
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115520
Table 2 Clinical characteristics of antidepressant poisoning in poisoning group, n (%)/mean ± SD
Clinical characteristic
Poisoning group (n = 28)
Drug type
    SSRI class17 (60.7)
    SNRI class7 (25.0)
    Tricyclic class4 (14.3)
Dosage taken
    < 3 times therapeutic dose4 (14.3)
    3-5 times therapeutic dose6 (21.4)
    ≥ 5 times therapeutic dose18 (64.3)
Presentation time
    < 2 hours5 (17.9)
    2-6 hours20 (71.4)
    > 6 hours3 (10.7)
Poisoning severity
    Mild16 (57.1)
    Moderate9 (32.1)
    Severe3 (10.7)
Main clinical symptoms
    Nausea and vomiting25 (89.3)
    Dizziness and headache22 (78.6)
    Somnolence19 (67.9)
    Palpitations15 (53.6)
    Consciousness disorder8 (28.6)
    Convulsions3 (10.7)
Treatment regimen
    Gastric lavage + activated charcoal24 (85.7)
    Symptomatic supportive treatment28 (100.0)
    Blood purification3 (10.7)
    Mechanical ventilation2 (7.1)
Cause of poisoning
    Suicidal intent23 (82.1)
    Accidental poisoning3 (10.7)
    Drug abuse2 (7.1)
Past history
    Psychiatric disease history20 (71.4)
    Antidepressant medication use history18 (64.3)
    Previous suicide attempt history7 (25.0)
    Other chronic disease history5 (17.9)
Abnormal laboratory findings
    Liver function abnormalities12 (42.9)
    ECG abnormalities16 (57.1)
    Electrolyte disorders8 (28.6)
    Hospital stays (days)4.3 ± 2.2


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