Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma

Table 8 Multiple linear regression analysis of factors affecting depressive symptoms

Variable	B	Standard error	β	t value	P value	95%CI
Constant	15.867	3.245	-	4.89	< 0.001	9.468-22.266
IL-6 (ln transformed)	2.186	0.324	0.365	6.75	< 0.001	1.547-2.825
CD4+ cell count	-0.008	0.002	-0.234	-4.12	< 0.001	-0.012 to -0.004
TNM stage	1.247	0.386	0.178	3.23	0.001	0.486-2.008
NLR (ln transformed)	1.834	0.567	0.198	3.24	0.001	0.716-2.952
Albumin	-0.156	0.078	-0.124	-2.00	0.047	-0.310 to -0.002

Model goodness of fit: R² = 0.524, adjusted R² = 0.512, F = 43.02, P < 0.001; variance inflation factor all < 3.0, no multicollinearity. IL-6: Interleukin-6; TNM: Tumor-node-metastasis; NLR: Neutrophil-to-lymphocyte ratio; CI: Confidence interval.