Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma

doi:10.5498/wjp.v16.i4.115490

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World Journal of Psychiatry

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2220-3206

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World J Psychiatry. Apr 19, 2026; 16(4): 115490
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115490

Table 5 Comparison of inflammatory and immune-related cytokines, mean ± SD

Indicator	Non-depression group (n = 89)	Depression group (n = 113)	t/Z value	P value
IL-6 (pg/mL), M (Q1, Q3)	4.2 (2.8, 7.1)	8.6 (5.3, 14.2)	-6.74	< 0.001
TNF-α (pg/mL), M (Q1, Q3)	12.4 (8.7, 18.3)	19.8 (14.2, 28.6)	-5.89	< 0.001
IL-10 (pg/mL)	8.3 ± 3.6	6.7 ± 3.2	3.26	0.001
IFN-γ (pg/mL)	15.8 ± 7.2	12.4 ± 6.8	3.42	0.001
CRP (mg/L), M (Q1, Q3)	5.8 (2.1, 12.4)	12.7 (6.8, 23.5)	-4.96	< 0.001
ESR (mm/hour), M (Q1, Q3)	28 (18, 42)	38 (25, 58)	-3.84	< 0.001

IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; IL-10: Interleukin-10; IFN-γ: Interferon-γ; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate.

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Citation: Dong S, Mou HL, Zhang H, Ye T. Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma. World J Psychiatry 2026; 16(4): 115490
URL: https://www.wjgnet.com/2220-3206/full/v16/i4/115490.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i4.115490

Dong S, Mou HL, Zhang H, Ye T. Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma. World J Psychiatry 2026; 16(4): 115490 [DOI: 10.5498/wjp.v16.i4.115490]

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