Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma

doi:10.5498/wjp.v16.i4.115490

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Apr 19, 2026; 16(4): 115490
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115490

Table 3 Comparison of cellular immune indicators, mean ± SD

Indicator	Non-depression group (n = 89)	Depression group (n = 113)	t/Z value	P value
CD3+ cell count (cells/μL)	1486 ± 428	1267 ± 396	3.68	< 0.001
CD3+ cell percentage (%)	68.2 ± 9.8	64.7 ± 11.2	2.31	0.022
CD4+ cell count (cells/μL)	894 ± 287	736 ± 253	4.02	< 0.001
CD4+ cell percentage (%)	40.8 ± 7.6	37.2 ± 8.4	3.14	0.002
CD8+ cell count (cells/μL)	542 ± 198	486 ± 176	2.09	0.038
CD8+ cell percentage (%)	24.7 ± 6.2	25.8 ± 7.1	-1.15	0.252
CD4+/CD8+ ratio	1.72 ± 0.48	1.51 ± 0.52	2.94	0.004
NK cell count (cells/μL)	387 ± 142	325 ± 128	3.24	0.001
NK cell percentage (%)	17.8 ± 6.4	15.2 ± 5.9	2.98	0.003
B cell count (cells/μL)	248 ± 89	221 ± 76	2.27	0.024
B cell percentage (%)	11.3 ± 4.2	10.6 ± 3.8	1.23	0.220

NK: Natural killer.

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Citation: Dong S, Mou HL, Zhang H, Ye T. Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma. World J Psychiatry 2026; 16(4): 115490
URL: https://www.wjgnet.com/2220-3206/full/v16/i4/115490.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i4.115490

Dong S, Mou HL, Zhang H, Ye T. Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma. World J Psychiatry 2026; 16(4): 115490 [DOI: 10.5498/wjp.v16.i4.115490]

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