Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma

Table 1 Comparison of patient baseline characteristics, n (%)/mean ± SD

Characteristic	Total (n = 202)	Non-depression group (n = 89)	Depression group (n = 113)	χ2/t value	P value
Demographic characteristics
Age (years)	57.3 ± 13.8	55.8 ± 14.2	58.4 ± 13.5	-1.32	0.188
Gender
Male	117 (57.9)	49 (55.1)	68 (60.2)	0.68	0.410
Female	85 (42.1)	40 (44.9)	45 (39.8)
Education level
Middle school and below	76 (37.6)	27 (30.3)	49 (43.4)	8.42	0.038
High school/technical school	89 (44.1)	42 (47.2)	47 (41.6)
College and above	37 (18.3)	20 (22.5)	17 (15.0)
Marital status
Married	154 (76.2)	72 (80.9)	82 (72.6)	2.15	0.143
Single/divorced/widowed	48 (23.8)	17 (19.1)	31 (27.4)
Employment status
Employed	98 (48.5)	50 (56.2)	48 (42.5)	6.78	0.034
Retired	67 (33.2)	28 (31.5)	39 (34.5)
Unemployed/jobless	37 (18.3)	11 (12.4)	26 (23.0)
Disease characteristics
Pathological type
Superficial spreading	126 (62.4)	59 (66.3)	67 (59.3)	4.89	0.180
Nodular	51 (25.2)	19 (21.3)	32 (28.3)
Acral lentiginous	18 (8.9)	8 (9.0)	10 (8.8)
Others	7 (3.5)	3 (3.4)	4 (3.5)
TNM stage
Stage I	45 (22.3)	26 (29.2)	19 (16.8)	7.89	0.048
Stage II	78 (38.6)	36 (40.4)	42 (37.2)
Stage III	58 (28.7)	21 (23.6)	37 (32.7)
Stage IV	21 (10.4)	6 (6.7)	15 (13.3)
Breslow thickness (mm)	3.8 ± 2.6	3.2 ± 2.3	4.3 ± 2.8	-2.86	0.005
Ulceration
Present	89 (44.1)	32 (36.0)	57 (50.4)	4.92	0.027
Absent	113 (55.9)	57 (64.0)	56 (49.6)
Lymph node metastasis
Present	79 (39.1)	27 (30.3)	52 (46.0)	8.95	0.003
Absent	123 (60.9)	62 (69.7)	61 (54.0)
General condition
BMI (kg/m2)	23.7 ± 4.2	24.1 ± 3.8	23.4 ± 4.5	1.12	0.264
ECOG score
0 points	78 (38.6)	43 (48.3)	35 (31.0)	12.86	0.002
1 point	89 (44.1)	38 (42.7)	51 (45.1)
2 points	35 (17.3)	8 (9.0)	27 (23.9)
Comorbidities
Hypertension	68 (33.7)	26 (29.2)	42 (37.2)	3.68	0.159
Diabetes	32 (15.8)	12 (13.5)	20 (17.7)
Coronary heart disease	21 (10.4)	7 (7.9)	14 (12.4)
Others	15 (7.4)	6 (6.7)	9 (8.0)
None	66 (32.7)	38 (42.7)	28 (24.8)

TNM: Tumor-node-metastasis; BMI: Body mass index; ECOG: Eastern Cooperative Oncology Group.