Risk factors associated with anxiety and depression in patients with inflammatory bowel disease identified using structural equation modeling

Table 2 Univariate analysis of factors influencing anxiety and depression in patients, median (interquartile rage)

Variable	n	HADS score	t/F	P value
Age			40.605	< 0.001
≥ 18 years	77	22.00 (14.00-25.00)
≥ 40 years	82	17.00 (14.00-19.00)
≥ 60 years	88	14.00 (13.00-16.00)
Sex			62.748	< 0.001
Male	122	14.00 (12.75-16.00)
Female	125	19.00 (15.00-23.00)
BMI (kg/m2)			2.184	0.336
< 18.5	12	18.50 (14.00-22.00)
18.5-23.9	206	16.00 (13.00-20.00)
≥ 24.0	29	14.00 (13.00-18.50)
Course			1.066	0.302
< 1 year	109	15.00 (13.00-20.00)
≥ 1 year	138	16.00 (13.00-20.25)
Disease classification			1.345	0.246
Crohn’s disease	163	15.00 (14.00-21.00)
Ulcerative colitis	84	15.00 (13.00-19.75)
Working condition			183.325	< 0.001
Employed	114	13.00 (12.00-14.00)
Unemployed	133	20.00 (17.00-24.00)
Place of abode			0.089	0.766
Urban	173	16.00 (13.00-20.00)
Rural	74	15.00 (14.00-20.00)
Standard of culture			3.431	0.180
≤ Junior high	72	15.00 (13.00-21.00)
High school/vocational	85	16.00 (14.00-21.00)
≥ College	90	14.00 (13.00-18.00)
Marital status			93.130	< 0.001
Married	89	13.00 (12.00-14.00)
Unmarried	97	18.00 (15.00-20.00)
Divorced/widowed	61	23.00 (15.00-25.00)
Average monthly household income			138.564	< 0.001
< 3000 yuan	119	13.00 (12.00-18.00)
≥ 3000 yuan	128	19.00 (16.25-23.75)
Use of biological agents			0.245	0.620
Yes	185	15.00 (13.00-20.00)
No	62	16.00 (13.00-22.00)
Disease stage			144.762	< 0.001
Remission	142	14.00 (12.75-14.00)
Active	105	21.00 (18.00-24.50)
Medical insurance			0.000	0.990
Yes	178	15.00 (13.00-20.00)
No	69	15.00 (13.00-21.00)

BMI: Body mass index; HADS: Hospital Anxiety and Depression Scale.