Monitoring white matter volume alterations via cranial magnetic resonance imaging in major depressive disorder: Association with cognitive dysfunction

Table 7 Correlations of regional fractional anisotropy and mean kurtosis with cognitive metrics

	MoCA		TMT-A		TMT-B		DSST
	r value	P value	r value	P value	r value	P value	r value	P value
FA value
Left temporal lobe	-0.002	0.984	0.098	0.391	0.013	0.905	0.069	0.523
Right temporal lobe	0.095	0.384	-0.117	0.283	0.049	0.652	0.100	0.358
MK value
Left superior frontal gyrus	0.331	0.002	0.033	0.760	0.018	0.866	-0.265	0.014
Right superior frontal gyrus	0.422	< 0.0001	-0.117	0.284	-0.140	0.197	0.081	0.459
Left temporal lobe	-0.092	0.401	-0.089	0.413	-0.111	0.307	0.076	0.486
Right temporal lobe	0.048	0.657	0.096	0.378	0.073	0.504	-0.172	0.114

FA: Fractional anisotropy; MK: Mean kurtosis; MoCA: Montreal Cognitive Assessment; TMT-A: Trail Making Test Part A; TMT-B: Trail Making Test Part B; DSST: Digit Symbol Substitution Test.