Copyright: ©Author(s) 2026.
World J Psychiatry. Apr 19, 2026; 16(4): 115192
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115192
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115192
Table 4 Comparative analysis of fractional anisotropy across brain regions, mean ± SD
| Groups | Left superior frontal gyrus | Right superior frontal gyrus | Left middle frontal gyrus | Right middle frontal gyrus | Left inferior frontal gyrus | Right inferior frontal gyrus |
| Observation group (n = 86) | 0.48 ± 0.10 | 0.46 ± 0.08 | 0.40 ± 0.05 | 0.38 ± 0.10 | 0.42 ± 0.08 | 0.44 ± 0.06 |
| Control group (n = 50) | 0.50 ± 0.05 | 0.48 ± 0.05 | 0.42 ± 0.06 | 0.40 ± 0.09 | 0.41 ± 0.06 | 0.46 ± 0.05 |
| t value | 1.320 | 0.364 | 2.088 | 1.166 | 0.767 | 1.989 |
| P value | 0.189 | 0.716 | 0.039 | 0.246 | 0.444 | 0.049 |
| Groups | Left temporal lobe | Right temporal lobe | Left occipital lobe | Right occipital lobe | Genu of the corpus callosum | Splenium of the corpus callosum |
| Observation group (n = 86) | 0.40 ± 0.06 | 0.38 ± 0.06 | 0.48 ± 0.07 | 0.48 ± 0.07 | 0.80 ± 0.09 | 0.80 ± 0.05 |
| Control group (n = 50) | 0.46 ± 0.04 | 0.50 ± 0.09 | 0.46 ± 0.05 | 0.50 ± 0.10 | 0.79 ± 0.09 | 0.79 ± 0.04 |
| t value | 6.299 | 9.316 | 1.773 | 1.367 | 0.625 | 1.207 |
| P value | < 0.0001 | < 0.0001 | 0.078 | 0.174 | 0.533 | 0.230 |
- Citation: Liu L, Tang S, Chen MZ, Nie X, Li J, Yao L, Zeng BG, Zhou JB, Zhou FQ. Monitoring white matter volume alterations via cranial magnetic resonance imaging in major depressive disorder: Association with cognitive dysfunction. World J Psychiatry 2026; 16(4): 115192
- URL: https://www.wjgnet.com/2220-3206/full/v16/i4/115192.htm
- DOI: https://dx.doi.org/10.5498/wjp.v16.i4.115192