Monitoring white matter volume alterations via cranial magnetic resonance imaging in major depressive disorder: Association with cognitive dysfunction

Table 2 Comparative Hamilton Depression Rating Scale assessment, mean ± SD

	Observation group (n = 86)	Control group (n = 50)	t value	P value
Depression	3.77 ± 0.50	1.66 ± 0.66	21.04	< 0.0001
Anxiety	3.81 ± 0.39	1.82 ± 0.72	20.92	< 0.0001
Sleep disorders	3.44 ± 0.57	1.56 ± 0.58	18.43	< 0.0001
Loss of appetite	3.64 ± 0.51	1.74 ± 0.49	21.25	< 0.0001
Guilt	3.55 ± 0.55	1.20 ± 0.95	18.29	< 0.0001
Suicidal thoughts	3.47 ± 0.52	0.81 ± 0.58	27.56	< 0.0001
Physical symptoms	3.69 ± 0.27	1.08 ± 0.44	42.90	< 0.0001
Global	25.36 ± 0.65	9.90 ± 1.54	81.59	< 0.0001