Risk characteristics of obesity and atherosclerotic cardiovascular events in patients with schizophrenia: A single-center 10-year retrospective cohort study

Table 5 Incident cardiovascular events during 10-year follow-up at our institution, n (%)/hazard ratio (95% confidence interval)

Outcome	Total events	Incidence rate per 1000 person-years	Obese	P value
Primary composite outcome
MACE	1842 (18.4)	23.6	2.34 (2.11-2.59)	< 0.001
Individual components
Cardiovascular death	423 (4.2)	5.4	2.67 (2.18-3.27)	< 0.001
Myocardial infarction	678 (6.8)	8.7	2.23 (1.89-2.63)	< 0.001
Stroke	543 (5.4)	6.9	1.98 (1.64-2.39)	< 0.001
Heart failure hospitalization	456 (4.6)	5.8	2.89 (2.36-3.54)	< 0.001
Coronary revascularization	234 (2.3)	3.0	2.12 (1.61-2.79)	< 0.001
Secondary outcomes
All-cause mortality	1234 (12.3)	15.8	1.89 (1.68-2.13)	< 0.001
New-onset diabetes	1456 (17.8)1	22.9	3.12 (2.77-3.51)	< 0.001
New-onset hypertension	1876 (28.6)2	37.5	2.45 (2.21-2.71)	< 0.001

¹Among 8157 without baseline diabetes at our hospital.

²Among 6544 without baseline hypertension at our hospital.

MACE: Major adverse cardiovascular events.