Clinical symptom improvement following modified electroconvulsive therapy is associated with modulation of peripheral inflammatory markers in schizophrenia

doi:10.5498/wjp.v16.i3.114036

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Mar 19, 2026; 16(3): 114036
Published online Mar 19, 2026. doi: 10.5498/wjp.v16.i3.114036

Table 2 Comparison of Positive and Negative Syndrome Scale scores and inflammatory markers

	Before MECT	After MECT	Statistical analysis
	mean ± SD	mean ± SD	Z	P value
PANSS	94.85 (14.02)	57.05 (12.89)	21.557	< 0.001
MLR	0.30 (0.20)	0.24 (0.18)	8.486	< 0.001
NLR	3.42 (2.27)	2.59 (2.23)	10.089	< 0.001
PLR	161.67 (116.03)	167.59 (124.73)	3.303	< 0.001
SII	763.01 (595.37)	586.36 (470.14)	8.291	< 0.001

MECT: Modified electroconvulsive therapy; PANSS: Positive and Negative Syndrome Scale; MLR: Monocyte-to-lymphocyte ratio; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; SII: Systemic immune-inflammatory index.

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Citation: Hou L, Chen R, Huang CB, Shi WJ, Wu LL. Clinical symptom improvement following modified electroconvulsive therapy is associated with modulation of peripheral inflammatory markers in schizophrenia. World J Psychiatry 2026; 16(3): 114036
URL: https://www.wjgnet.com/2220-3206/full/v16/i3/114036.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i3.114036

Hou L, Chen R, Huang CB, Shi WJ, Wu LL. Clinical symptom improvement following modified electroconvulsive therapy is associated with modulation of peripheral inflammatory markers in schizophrenia. World J Psychiatry 2026; 16(3): 114036 [DOI: 10.5498/wjp.v16.i3.114036]

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