Serum folate and brain-derived neurotrophic factor in pediatric autism spectrum disorder and their predictive role in illness severity

Table 1 Patients’ demographic information, n (%)

Data	Control group (n = 50)	Research group (n = 53)	t/χ2	P value
Gender			0.918	0.338
Male	32 (64.00)	29 (54.72)
Female	18 (36.00)	24 (45.28)
Age (years)	7.34 ± 1.57	7.06 ± 1.26	1.001	0.319
Disease duration (months)	5.88 ± 2.58	6.04 ± 2.85	0.298	0.766
Family genetic history			2.443	0.118
No	43 (86.00)	39 (73.58)
Yes	7 (14.00)	14 (26.42)
Severity
Mild to moderate	-	28 (52.83)
Severe	-	25 (47.17)
Father's personality			0.240	0.887
Introverted	15 (30.00)	17 (32.08)
Ambiverted	10 (20.00)	12 (22.64)
Extroverted	25 (50.00)	24 (45.28)
Mother's personality			0.404	0.817
Introverted	13 (26.00)	15 (28.30)
Ambiverted	20 (40.00)	18 (33.96)
Extroverted	17 (34.00)	20 (37.74)

For reference, parental personalities were evaluated through the Eysenck’s Personality Questionnaire-revised designed for adults[23]. In this assessment, the E (extraversion-introversion) dimension grouped participants into introverted, ambiverted, or extroverted categories.