Predictive role of family dysfunction on psychological morbidity in breast cancer patients

Table 4 Univariate analysis of risk factors for psychological morbidity, n (%)

Risk factor	Normal psychological health (n = 167)	Psychological problems (n = 118)	OR (95%CI)	χ2 value	P value
Demographic factors
Age
> 50 years	106 (63.5)	61 (51.7)	1.00 (reference)	4.12	0.042
≤ 50 years	61 (36.5)	57 (48.3)	1.58 (1.02-2.44)		0.041
Education level
> High school	117 (70.1)	69 (58.5)	1.00 (reference)	5.34	0.021
≤ High school	50 (29.9)	49 (41.5)	1.71 (1.09-2.69)		0.020
Employment status
Employed/retired	140 (83.8)	83 (70.3)	1.00 (reference)	8.23	0.004
Unemployed	18 (10.8)	24 (20.3)	2.14 (1.28-3.57)		0.004
Other	9 (5.4)	11 (9.3)	1.67 (0.89-3.12)		0.112
Household income
≥ 5000 yuan/month	91 (54.5)	47 (39.8)	1.00 (reference)	7.89	0.005
< 5000 yuan/month	76 (45.5)	71 (60.2)	1.89 (1.21-2.95)		0.005
Marital status
Married	137 (82.0)	87 (73.7)	1.00 (reference)	3.21	0.073
Unmarried/divorced/widowed	30 (18.0)	31 (26.3)	1.63 (0.95-2.78)		0.077
Residence
Urban	123 (73.7)	80 (67.8)	1.00 (reference)	1.23	0.267
Rural	44 (26.3)	38 (32.2)	1.33 (0.81-2.18)		0.259
Disease-related factors
TNM stage
Early stage (I-II)	119 (71.3)	66 (55.9)	1.00 (reference)	7.34	0.007
Advanced stage (III-IV)	48 (28.7)	52 (44.1)	2.31 (1.47-3.63)		< 0.001
Molecular subtype
Luminal A/B	129 (77.2)	81 (68.6)	1.00 (reference)	8.92	0.030
HER2-positive	24 (14.4)	21 (17.8)	1.39 (0.75-2.58)		0.291
Triple-negative	14 (8.4)	16 (13.6)	2.67 (1.35-5.28)		0.005

OR: Odds ratio; CI: Confidence interval; TNM: Tumor-node-metastasis-based; HER2: Human epidermal receptor 2.