Aberrant topology of the default mode network is associated with phosphatidylcholine and triglyceride levels in major depressive disorder

Table 4 Abnormal topological properties of the default mode network nodes in patients with major depressive disorder

Nodal metrics	Node	P value	FDR q value
Betweenness centrality	SFGmed.R	0.002	0.019a
	PCG.R	< 0.001c	0.011a
	SMG.L	0.016	0.049a
	SMG.R	0.012	0.049a
	ANG.L	0.004	0.021a
Degree centrality	SFGmed.R	< 0.001c	0.005a
	SMG.L	0.019	0.153
Clustering coefficient	PCG.R	0.002	0.029a
	SMG.L	0.034	0.108
	SMG.R	0.020	0.108
	ANG.L	0.025	0.108
	ANG.R	0.029	0.108
Efficiency	SFGmed.R	< 0.001c	0.005a
	SMG.L	0.014	0.114
Local efficiency	PCG.R	0.002	0.029a
	SMG.L	0.034	0.108
	SMG.R	0.020	0.108
	ANG.L	0.025	0.108
	ANG.R	0.029	0.108
Shortest path	SFGmed.R	< 0.001c	0.005a
	SMG.L	0.014	0.109

^aq < 0.05.

^cP < 0.001.

Only uncorrected P values with a threshold of < 0.05 are presented. False discovery rate correction was performed solely on the P values of the 16 default mode network nodes. FDR: False discovery rate; SFGmed.R: Right medial superior frontal gyrus; PCG.R: Right posterior cingulate gyrus; SMG.L: Left supramarginal gyrus; SMG.R: Right supramarginal gyrus; ANG.L: Left angular gyrus; ANG.R: Right angular gyrus.