Aberrant topology of the default mode network is associated with phosphatidylcholine and triglyceride levels in major depressive disorder

doi:10.5498/wjp.v16.i2.113513

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 2

This Article

(28)

(62)

(0)

(17)

(698)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Psychiatry

ISSN

2220-3206

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Psychiatry. Feb 19, 2026; 16(2): 113513
Published online Feb 19, 2026. doi: 10.5498/wjp.v16.i2.113513

Table 3 Demographic characteristics, mean ± SD

	MDD (n = 71)	HC (n = 76)	t/χ²	P value
Age	31.52 ± 11.63	30.68 ± 8.71	0.496	0.621
Education (years)	13.07 ± 3.15	15.62 ± 3.07	-4.960	< 0.001^c
Sex (male/female)	27/44	35/41	0.969	0.325
BMI (kg/m²)	22.56 ± 4.21	22.81 ± 4.55	-0.345	0.730
HAMA	19.69 ± 5.69	-	-	-
HAMD-17	21.59 ± 5.62	-	-	-
Total disease duration (months)	52.44 ± 53.0	-	-	-
Average daily dose (mg)	21.12 ± 12.92	-	-	-
SSRI/SNRI/NaSSA/SARI	34/21/9/7	-	-	-

^cP < 0.001.

Antidepressants were converted into fluoxetine equivalents. MDD: Major depressive disorder group; HC: Health control group; BMI: Body mass index; HAMA: Hamilton Anxiety Rating Scale; HAMD-17: 17-item Hamilton Depression Rating Scale; SSRI: Selective serotonin reuptake inhibitor; SNRI: Serotonin-norepinephrine reuptake inhibitor; NaSSA: Noradrenergic and specific serotonergic antidepressant; SARI: Serotonin receptor antagonist and reuptake inhibitor.

Full Size Table

Citation: Ma YH, Wang XY, Wang WL, Zhang J, Liu XH, Li DX, Zhou ZH, Chen LM, Zhou HL. Aberrant topology of the default mode network is associated with phosphatidylcholine and triglyceride levels in major depressive disorder. World J Psychiatry 2026; 16(2): 113513
URL: https://www.wjgnet.com/2220-3206/full/v16/i2/113513.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i2.113513

Ma YH, Wang XY, Wang WL, Zhang J, Liu XH, Li DX, Zhou ZH, Chen LM, Zhou HL. Aberrant topology of the default mode network is associated with phosphatidylcholine and triglyceride levels in major depressive disorder. World J Psychiatry 2026; 16(2): 113513 [PMID: 41641219 DOI: 10.5498/wjp.v16.i2.113513]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.