L-shaped association between fasting blood glucose and comorbid anxiety in Chinese patients with first-episode untreated major depressive disorder

Table 2 Baseline characteristics between major depressive disorder comorbid anxiety and non-comorbid anxiety, n (%)

Variables	Comorbid anxiety (n =1380)	Non-comorbid anxiety (n = 338)	F/χ2/z	P value
Age (years)	34.96 ± 12.48	34.51 ± 12.25	0.346	0.556
Age at onset (years)	34.75 ± 12.35	34.29 ± 12.15	0.378	0.539
Duration of illness (months)	6.32 ± 4.68	6.26 ± 4.94	0.462	0.829
HAMD	30.84 ± 2.81	28.08 ± 2.35	278.199	< 0.001
HAMA	21.89 ± 2.95	16.31 ± 0.81	1190.192	< 0.001
FBG (mmol/L)	5.43 ± 0.66	5.28 ± 0.56	13.112	< 0.001
TSH (uIU/mL)	5.29 ± 2.69	4.19 ± 1.70	51.26	< 0.001
TPOAb (IU/L)	18.90 (12.62-38.12)	18.83 (13.03-26.96)	-7.097	< 0.001
TGAb (IU/L)	22.16 (15.10-54.45)	18.33 (13.03-26.96)	-5.051	< 0.001
FT3 (pmol/L)	4.91 ± 0.71	4.87 ± 0.77	1.198	0.274
FT4 (pmol/L)	16.72 ± 3.10	16.65 ± 3.07	0.135	0.713
TC (mmol/L)	5.35 ± 1.10	4.78 ± 0.99	78.589	< 0.001
TG (mmol/L)	2.20 ± 0.98	2.05 ± 0.99	5.539	0.019
HDL-C (mmol/L)	1.21 ± 0.29	1.24 ± 0.26	2.578	0.109
LDL-C (mmol/L)	3.06 ± 0.86	2.68 ± 0.78	55.443	< 0.001
BMI (kg/m2)	24.37 ± 1.93	24.37 ± 1.89	0.0001	0.991
Systolic pressure (mmHg)	120.1 ± 11.03	116.96 ± 10.05	22.692	< 0.001
Diastolic pressure (mmHg)	76.37 ± 6.81	74.23 ± 6.16	27.771	< 0.001
Gender			0.118	0.731
Male	475 (34.42)	113 (33.43)
Female	905 (65.58)	225 (66.57)
Education			2.399	0.494
Junior high school	332 (24.06)	81 (23.96)
Senior high school	602 (43.62)	158 (46.75)
College	371 (26.88)	78 (23.08)
Postgraduate	75 (5.44)	21 (6.21)
Marital status			0.320	0.572
Single	399 (28.91)	103 (30.47)
Marriage	981 (71.09)	235 (69.53)
Psychotic symptoms			43.788	< 0.001
No	1210 (87.68)	337 (99.70)
Yes	170 (12.32)	1 (0.30)
Suicide attempt			74.592	< 0.001
No	1045 (75.72)	327 (96.75)
Yes	335 (24.28)	11 (3.25)

HAMD: 17-item Hamilton Rating Scale for Depression; HAMA: 14-item Hamilton Anxiety Rating Scale; FBG: Fasting blood glucose; TSH: Thyroid-stimulating hormone; TGAb: Thyroglobulin antibody; TPOAb: Thyroid peroxidase antibody; FT3 and FT4: Free triiodothyronine and thyroxine, respectively; TC: Total cholesterol; HDL-C: High density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; TG: Triglyceride; BMI: Body mass index.