Electroencephalogram-guided anesthesia and postoperative anxiety and depression in elderly gastric cancer patients with sleep disorders

Figure 1 Effects of electroencephalogram-guided anesthesia. A: Anesthetic drug-sparing effect of electroencephalogram (EEG)-guided anesthesia in elderly gastric cancer patients. The bar chart compares anesthetic drug dosages between EEG-guided anesthesia and conventional monitoring groups, showing consistently lower drug requirements in the EEG group across all four measured anesthetics (propofol, remifentanil, cisatracurium, and sevoflurane). Statistical analysis revealed significantly reduced dosage needs (P < 0.05) in the EEG-monitored patients for all anesthetic agents, demonstrating the drug-sparing effect of EEG-guided individualized anesthesia in elderly gastric cancer patients with preoperative sleep disorders, ^aP < 0.05; B: Effects of EEG-guided anesthesia on postoperative anxiety and depression scores in elderly gastric cancer patients with sleep disorders. The bar chart illustrates significantly lower postoperative anxiety and depression scores in the EEG-guided anesthesia group compared to the control group across all assessment timepoints, with consistent improvements in both Hospital Anxiety and Depression Scale (HADS)-A and HADS-D subscales. Statistical analysis reveals highly significant differences (P < 0.05) between groups at both postoperative day 3 and 1-month follow-up, demonstrating that EEG-guided individualized anesthesia provides sustained psychological benefits for elderly gastric cancer patients with preoperative sleep disorders, ^aP < 0.05. EEG: Electroencephalogram; HADS: Hospital Anxiety and Depression Scale; MAC: Minimum alveolar concentration; POD3: Postoperative day 3.