Systemic immune-inflammation index and postoperative anxiety after transforaminal endoscopic lumbar discectomy

doi:10.5498/wjp.123546

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Nov 19, 2026; 16(11): 123546
Published online Nov 19, 2026. doi: 10.5498/wjp.123546

Table 5 Spearman’s rank correlation analysis between inflammatory/immune markers and Hospital Anxiety and Depression Scale-Anxiety subscale scores

Variable	Correlation coefficient (r)	P value
Postoperative SII	0.412	< 0.001
Postoperative TNF-α	0.368	< 0.001
Postoperative IL-6	0.445	< 0.001
Postoperative CRP	0.398	< 0.001
Postoperative PCT	0.286	< 0.001
Preoperative RF	0.168	0.024
Postoperative IgG	-0.124	0.097
Postoperative IgA	-0.038	0.614
Postoperative IgM	-0.021	0.782

SII: Systemic immune-inflammation index; TNF-α: Tumor necrosis factor alpha; IL-6: Interleukin-6; PCT: Procalcitonin; CRP: C-reactive protein; RF: Rheumatoid factor; IgG: Immunoglobulin G; IgA: Immunoglobulin A; IgM: Immunoglobulin M.

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Citation: Zeng LS, Yang Q, Yang G. Systemic immune-inflammation index and postoperative anxiety after transforaminal endoscopic lumbar discectomy. World J Psychiatry 2026; 16(11): 123546
URL: https://www.wjgnet.com/2220-3206/full/v16/i11/123546.htm
DOI: https://dx.doi.org/10.5498/wjp.123546

Zeng LS, Yang Q, Yang G. Systemic immune-inflammation index and postoperative anxiety after transforaminal endoscopic lumbar discectomy. World J Psychiatry 2026; 16(11): 123546 [DOI: 10.5498/wjp.123546]

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