Impact of multicomponent, nonpharmacological care program for mild Alzheimer’s disease with anxiety and depression

doi:10.5498/wjp.123323

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Nov 19, 2026; 16(11): 123323
Published online Nov 19, 2026. doi: 10.5498/wjp.123323

Table 5 Comparison of cognitive function between two groups (points), mean ± SD

Parameter	Conventional group (n = 104)	Multicomponent group (n = 96)	t value	P value
MMSE scores
Baseline	20.28 ± 2.52	20.41 ± 2.48	0.353	0.725
3 months	19.92 ± 2.81	21.06 ± 2.67	2.935	0.004
ADAS-cog scores
Baseline	23.15 ± 6.42	22.68 ± 6.96	0.502	0.616
3 months	24.03 ± 6.77	21.92 ± 6.25	2.282	0.024

MMSE: Mini-Mental State Examination; ADAS-cog: Alzheimer’s disease Assessment Scale-Cognitive Subscale.

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Citation: Chen YF, Zhu Y, Li BX, Zhang JN. Impact of multicomponent, nonpharmacological care program for mild Alzheimer’s disease with anxiety and depression. World J Psychiatry 2026; 16(11): 123323
URL: https://www.wjgnet.com/2220-3206/full/v16/i11/123323.htm
DOI: https://dx.doi.org/10.5498/wjp.123323

Chen YF, Zhu Y, Li BX, Zhang JN. Impact of multicomponent, nonpharmacological care program for mild Alzheimer’s disease with anxiety and depression. World J Psychiatry 2026; 16(11): 123323 [DOI: 10.5498/wjp.123323]

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