Anxiety-depression after intravascular ultrasound-guided drug-coated balloon angioplasty dissection: Predictors and 12-month cardiovascular outcomes

Table 4 Laboratory biomarkers on post-procedural day 14, mean ± SD

Biomarker	Anxiety-depression cohort (n = 65)	Stable cohort (n = 103)	P value
hs-CRP (mg/L)	12.8 ± 4.5	6.2 ± 2.8	< 0.001
IL-6 (pg/mL)	9.5 ± 3.2	5.2 ± 1.8	< 0.001
TNF-α (pg/mL)	15.2 ± 4.0	9.8 ± 2.5	< 0.001
NLR	4.8 ± 1.6	2.9 ± 1.1	< 0.001
Fibrinogen (g/L)	4.2 ± 0.8	3.5 ± 0.6	< 0.001
Peak hs-TnI (ng/mL)	0.85 ± 0.32	0.42 ± 0.18	< 0.001
NT-proBNP (pg/mL)	385 ± 125	245 ± 88	< 0.001
Peak CK-MB (U/L)	28.5 ± 10.2	18.2 ± 6.5	< 0.001
Morning cortisol (nmol/L)	418 ± 98	325 ± 72	< 0.001
ACTH (pg/mL)	42.5 ± 9.2	35.2 ± 7.0	< 0.001
Homocysteine (μmol/L)	16.8 ± 5.5	12.2 ± 3.8	< 0.001
HbA1c (%)	6.5 ± 1.2	6.2 ± 1.0	0.082
LDL-C (mmol/L)	2.85 ± 0.82	2.72 ± 0.75	0.385
HDL-C (mmol/L)	1.02 ± 0.25	1.18 ± 0.28	0.012

hs-CRP: High-sensitivity C-reactive protein; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; NLR: Neutrophil-to-lymphocyte ratio; hs-TnI: High-sensitivity troponin I; NT-proBNP: N-terminal pro-B-type natriuretic peptide; CK-MB: Creatine kinase-MB; ACTH: Adrenocorticotropic hormone; HbA1c: Glycated hemoglobin; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol.