Psychiatric symptoms in patients with lung cancer following postoperative acute respiratory distress syndrome

Table 7 Exploratory multivariable logistic regression models for anxiety, depression, and sleep disturbance

Outcome	Variables	β	SE	OR (95%CI)	P value
Anxiety	Female sex	0.742	0.365	2.100 (1.027-4.294)	0.042
Anxiety	Severe acute respiratory distress syndrome	0.982	0.452	2.669 (1.102-6.461)	0.030
Anxiety	Postoperative delirium	0.908	0.421	2.480 (1.087-5.658)	0.031
Depression	Severe acute respiratory distress syndrome	1.188	0.471	3.281 (1.304-8.259)	0.012
Depression	Postoperative delirium	0.859	0.438	2.361 (1.000-5.574)	0.050
Sleep disturbance	Severe acute respiratory distress syndrome	1.416	0.427	4.121 (1.783-9.523)	0.001
Sleep disturbance	Thoracotomy	0.904	0.367	2.470 (1.204-5.068)	0.014
Sleep disturbance	Postoperative pain NRS ≥ 5 points	0.802	0.346	2.230 (1.132-4.394)	0.020
Sleep disturbance	Mechanical ventilation time ≥ 5 days	0.658	0.329	1.931 (1.014-3.678)	0.045
Sleep disturbance	Postoperative delirium	0.772	0.389	2.164 (1.010-4.635)	0.047

Each outcome-specific model was adjusted for clinically relevant variables selected from the a priori domains. These exploratory models were based on retrospective clinical data and should be interpreted as exploratory findings. OR: Odds ratio; CI: Confidence interval; NRS: Numerical Rating Scale.