Serum proprotein convertase subtilisin/kexin type 9 levels correlate with depression severity in post-stroke patients

doi:10.5498/wjp.122026

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Nov 19, 2026; 16(11): 122026
Published online Nov 19, 2026. doi: 10.5498/wjp.122026

Table 6 Correlations between serum proprotein convertase subtilisin/kexin type 9 concentrations and clinical outcomes

Correlation analysis	Pearson r	P value
PCSK9 vs HAMD-17 at baseline	0.428	< 0.001
PCSK9 vs HAMD-17 at 4 weeks	0.512	< 0.001
PCSK9 vs HAMD-17 at 8 weeks	0.589	< 0.001
PCSK9 vs HAMD-17 at 12 weeks	0.652	< 0.001
PCSK9 vs HAMA at 12 weeks	0.587	< 0.001
PCSK9 vs IL-6 at 12 weeks	0.543	< 0.001
PCSK9 vs TNF-α at 12 weeks	0.498	< 0.001
PCSK9 vs MoCA at 12 weeks	-0.456	< 0.001

PCSK9: Proprotein convertase subtilisin/kexin type 9; HAMD-17: 17-item Hamilton Depression Rating Scale; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; MoCA: Montreal Cognitive Assessment; HAMA: Hamilton Anxiety Scale.

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Citation: Song HY, Yang Y, Sun XY, Zhang MJ, Wang SG. Serum proprotein convertase subtilisin/kexin type 9 levels correlate with depression severity in post-stroke patients. World J Psychiatry 2026; 16(11): 122026
URL: https://www.wjgnet.com/2220-3206/full/v16/i11/122026.htm
DOI: https://dx.doi.org/10.5498/wjp.122026

Song HY, Yang Y, Sun XY, Zhang MJ, Wang SG. Serum proprotein convertase subtilisin/kexin type 9 levels correlate with depression severity in post-stroke patients. World J Psychiatry 2026; 16(11): 122026 [DOI: 10.5498/wjp.122026]

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