Development and validation of a nomogram model for identifying post-stroke anxiety symptoms

doi:10.5498/wjp.122517

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Oct 19, 2026; 16(10): 122517
Published online Oct 19, 2026. doi: 10.5498/wjp.122517

Table 2 Comparison of clinical characteristics between the training and validation sets, n (%)

Variables	Validation set (n = 285)	Training set (n = 662)	Z/χ²	P value
NIHSS score	2.00 (1.00, 4.00)	2.00 (1.00, 4.00)	-0.27	0.787
mRS score	2.00 (1.00, 3.00)	2.00 (1.00, 3.00)	-0.26	0.793
Hcy	14.46 (11.18, 17.30)	13.85 (10.73, 17.78)	-0.91	0.363
TSH	2.03 (1.29, 3.36)	1.97 (1.19, 3.05)	-1.19	0.235
CRP	2.73 (1.00, 7.90)	2.70 (1.00, 7.75)	-0.09	0.932
Type of stroke	-	-	2.04	0.154
Ischemic stroke	253 (88.77)	607 (91.69)	-	-
Hemorrhagic stroke	32 (11.23)	55 (8.31)	-	-
TOAST classification	-	-	0.50	0.918
Undetermined etiologies	7 (2.77)	13 (2.15)	-	-
Large vessel atherosclerosis	173 (68.38)	417 (68.93)	-	-
Small vessel occlusion	61 (24.11)	142 (23.47)	-	-
Cardio-embolic source	12 (4.74)	33 (5.45)	-	-
Time since stroke	-	-	0.86	0.652
> 6 months	5 (1.75)	9 (1.36)	-	-
> 7 days ≤ 6 months	155 (54.39)	380 (57.40)	-	-
≤ 7 days	125 (43.86)	273 (41.24)	-	-
Feeling pain after stroke	-	-	0.10	0.754
yes	25 (8.77)	54 (8.16)	-	-
no	260 (91.23)	608 (91.84)	-	-
Pre-stroke sleep duration	-	-	2.72	0.437
< 5 hours	46 (16.14)	131 (19.79)	-	-
5-6 hours	41 (14.39)	94 (14.20)	-	-
6-7 hours	26 (9.12)	46 (6.95)	-	-
> 7 hours	172 (60.35)	391 (59.06)	-	-
History of hyperlipidemia	-	-	5.79	0.016^a
No	262 (91.93)	572 (86.40)	-	-
Yes	23 (8.07)	90 (13.60)	-	-
History of hemicrania	-	-	0.03	0.862
No	281 (98.60)	650 (98.19)	-	-
Yes	4 (1.40)	12 (1.81)	-	-
Family history of stroke	-	-	1.26	0.262
No	279 (97.89)	639 (96.53)	-	-
Yes	6 (2.11)	23 (3.47)	-	-
Depression	-	-	2.22	0.136
No	252 (88.42)	561 (84.74)	-	-
Yes	33 (11.58)	101 (15.26)	-	-
Anxiety	-	-	2.29	0.13
No	251 (88.07)	558 (84.29)	-	-
Yes	34 (11.93)	104 (15.71)	-	-

^aP < 0.05.

NIHSS: Neurological Institute of Health Stroke Scale; mRS: Modified Rankin Scale; Hcy: Homocysteine; TSH: Thyroid-stimulating hormone; CRP: C-reactive protein; TOAST: Trial of ORG 10172 in Acute Stroke Treatment.

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Citation: Luo SY, Feng L, Hong YJ, Liang J, Peng Y, Shao LH, Zhang XB. Development and validation of a nomogram model for identifying post-stroke anxiety symptoms. World J Psychiatry 2026; 16(10): 122517
URL: https://www.wjgnet.com/2220-3206/full/v16/i10/122517.htm
DOI: https://dx.doi.org/10.5498/wjp.122517

Luo SY, Feng L, Hong YJ, Liang J, Peng Y, Shao LH, Zhang XB. Development and validation of a nomogram model for identifying post-stroke anxiety symptoms. World J Psychiatry 2026; 16(10): 122517 [DOI: 10.5498/wjp.122517]

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