Determinants of psychological emotions in lung cancer patients and their correlations with tumor markers and inflammatory cytokines

Table 6 Comparison of tumor marker levels, mean ± SD

	CEA (ng/mL)	SCC-Ag (ng/mL)	NSE (ng/mL)	proGRP (pg/mL)	CYFRA21-1 (ng/mL)
Anxiety (n = 56)	59.97 ± 8.65	1.34 ± 0.34	27.00 ± 3.00	35.83 ± 5.70	10.43 ± 1.92
Non-anxiety (n = 72)	53.58 ± 6.83	1.29 ± 0.32	22.22 ± 3.04	34.43 ± 5.29	9.33 ± 2.26
t	4.678	0.897	8.869	1.433	2.914
P value	< 0.0001	0.371	< 0.0001	0.154	0.004
Depression (n = 51)	58.96 ± 9.11	1.26 ± 0.30	25.19 ± 3.92	34.36 ± 5.25	10.80 ± 2.11
Non-depression (n = 77)	54.66 ± 7.25	1.35 ± 0.34	23.73 ± 3.70	35.49 ± 5.64	9.15 ± 1.98
t	2.960	1.444	2.132	1.144	4.484
P value	0.004	0.151	0.035	0.255	< 0.0001

CEA: Carcinoembryonic antigen; SCC-Ag: Squamous cell carcinoma antigen; NSE: Neuron-specific enolase; proGRP: Pro-gastrin-releasing peptide; CYFRA21-1: Cytokeratin fragment antigen 21-1.