Prognostic factors of depression and anxiety in infertile women with cesarean scar defects

Table 6 Subgroup analysis: Psychological scores and assisted reproductive technology outcomes stratified by cesarean scar defect severity and pregnancy outcome, mean ± SD

Subgroup	SAS	SDS	FertiQoL	Pregnancy rate (%)	P (SAS/SDS)
Mild CSD (RMT ≥ 3.5 mm, n = 35)
Pregnant (n = 26)	52.8 ± 9.0	50.4 ± 8.6	58.9 ± 7.9	74.3	-
Non-pregnant (n = 9)	61.2 ± 9.8	59.1 ± 9.2	49.6 ± 8.4	25.7	0.028
Moderate CSD (RMT 2.5-3.4 mm, n = 37)
Pregnant (n = 20)	55.3 ± 9.8	52.8 ± 9.3	56.4 ± 8.8	54.1	-
Non-pregnant (n = 17)	64.1 ± 10.4	62.3 ± 10.1	46.8 ± 9.1	45.9	0.009
Severe CSD (RMT < 2.5 mm, n = 28)
Pregnant (n = 5)	58.0 ± 11.2	55.6 ± 10.4	53.2 ± 9.0	17.9	-
Non-pregnant (n = 23)	65.4 ± 10.8	65.0 ± 9.8	44.2 ± 9.6	82.1	0.018
P value (across CSD severity groups, non-pregnant only)
Between-group (non-pregnant)	0.048	0.039	0.044	-	One-way ANOVA

Values shown are the mean ± SD (psychological scores) or percentage (pregnancy rates). P values from independent-samples t-test [pregnant vs non-pregnant within each cesarean scar defect (CSD) stratum]. P values for between-group comparison across CSD severity strata (non-pregnant only) by one-way ANOVA. RMT: Residual myometrial thickness; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale; FertiQoL: Fertility Quality of Life; CSD: Cesarean scar defect.