Prognostic factors of depression and anxiety in infertile women with cesarean scar defects

Table 4 Univariate logistic regression analysis of candidate prognostic factors for clinical pregnancy

Variable	β	OR (95%CI)	SE	Wald (df = 1)	P value
Psychological variables
SAS score (per 1 point)	-0.067	0.935 (0.904-0.967)	0.016	17.24	< 0.001
SDS score (per 1 point)	-0.071	0.932 (0.901-0.963)	0.016	19.89	< 0.001
FertiQoL score (per 1 point)	0.083	1.087 (1.047-1.128)	0.020	17.61	< 0.001
Spousal support score	0.072	1.075 (1.037-1.114)	0.019	14.23	< 0.001
Co-morbid anxiety & depression	-1.601	0.202 (0.088-0.462)	0.421	14.47	< 0.001
CSD characteristics
Residual myometrium (mm)	0.621	1.861 (1.382-2.506)	0.152	16.73	< 0.001
CSD diameter (mm)	-0.158	0.854 (0.744-0.980)	0.070	5.09	0.024
CSD severity: Mild vs severe	2.417	11.21 (3.72-33.79)	0.565	18.27	< 0.001
Infertility & ART variables
Infertility duration (years)	-0.225	0.799 (0.665-0.959)	0.094	5.74	0.017
Prior ART attempts (n)	-0.378	0.685 (0.494-0.949)	0.167	5.12	0.024
High-quality embryos (n)	0.189	1.208 (1.017-1.435)	0.088	4.62	0.032
Demographic variables
Age (years)	-0.071	0.932 (0.858-1.012)	0.042	2.86	0.091
BMI (kg/m²)	-0.039	0.962 (0.871-1.062)	0.050	0.60	0.438
Nursing intervention (comprehensive vs none)	1.005	2.732 (1.188-6.282)	0.427	5.54	0.019

All variables with P < 0.10 were entered into multivariate analysis. Dependent variable: Clinical pregnancy (1 = pregnant, 0 = non-pregnant). Reference for cesarean scar defect severity: Severe group. BMI: Body mass index; OR: Odds ratio; CI: Confidence interval; CSD: Cesarean scar defect; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale; FertiQoL: Fertility Quality of Life scale; ART: Assisted reproductive technology.