Impact of post-stroke depression on the prognosis of stroke-associated pneumonia and analysis of predictive factors: A retrospective study of 186 patients

Table 5 Independent predictors of adverse prognosis: Multivariable logistic regression

Variable	β	SE	Wald	OR (95%CI)	P value
APACHE II ≥ 18	1.238	0.302	16.82	3.45 (1.92-6.20)	< 0.001
Comorbid PSD	1.138	0.268	18.02	3.12 (1.85-5.26)	< 0.001
Albumin < 30 g/L	1.022	0.298	11.76	2.78 (1.55-4.98)	0.001
MV > 7 days	0.975	0.298	10.70	2.65 (1.48-4.75)	0.001
MDR organism	0.925	0.292	10.04	2.52 (1.42-4.47)	0.002
BDNF < 14.5 ng/mL	0.855	0.312	7.51	2.35 (1.28-4.32)	0.006
Age ≥ 75 years	0.683	0.278	6.03	1.98 (1.15-3.41)	0.014
Non-significant variables
IL-6 > 35 pg/mL	0.585	0.305	3.68	1.80 (0.99-3.26)	0.055
Cortisol > 380 nmol/L	0.498	0.298	2.79	1.65 (0.92-2.95)	0.095
NIHSS ≥ 10	0.455	0.285	2.55	1.58 (0.90-2.76)	0.110
Dysphagia	0.412	0.275	2.25	1.51 (0.88-2.58)	0.134
Diabetes mellitus	0.365	0.268	1.85	1.44 (0.85-2.43)	0.174
Corticosteroid use	0.328	0.302	1.18	1.39 (0.77-2.51)	0.278

Hosmer-Lemeshow test: χ² = 5.68, P = 0.682. OR: Odds ratio; 95%CI: 95% confidence interval; APACHE II: Acute Physiology and Chronic Health Evaluation II; PSD: Post-stroke depression; MV: Mechanical ventilation; MDR: Multi-drug resistant; BDNF: Brain-derived neurotrophic factor; IL-6: Interleukin-6; NIHSS: National Institutes of Health Stroke Scale.