Impact of post-stroke depression on the prognosis of stroke-associated pneumonia and analysis of predictive factors: A retrospective study of 186 patients

Table 2 Stroke-associated pneumonia clinical features and severity, mean ± SD or n (%)

SAP feature	Depression group (n = 92)	Non-depression group (n = 94)	P value
Onset to SAP (days)	3.2 ± 1.5	3.5 ± 1.8	0.226
APACHE II score	17.8 ± 4.5	13.2 ± 3.8	< 0.001
CURB-65 score	2.8 ± 0.9	2.1 ± 0.8	< 0.001
Pathogen distribution
Gram-negative bacilli	52 (56.5)	48 (51.1)	0.453
Gram-positive cocci	22 (23.9)	25 (26.6)	0.668
Fungi	12 (13.0)	8 (8.5)	0.323
Mixed infection	18 (19.6)	15 (16.0)	0.514
MDR organism	35 (38.0)	21 (22.3)	0.019
Bilateral involvement	48 (52.2)	33 (35.1)	0.019
Pleural effusion	26 (28.3)	14 (14.9)	0.026
Mechanical ventilation	60 (65.2)	40 (42.6)	0.002
MV duration (days)	8.5 ± 3.2	5.2 ± 2.1	< 0.001
ICU admission	55 (59.8)	38 (40.4)	0.008
ICU stay (days)	12.5 ± 4.8	8.2 ± 3.5	< 0.001
Tracheostomy	18 (19.6)	8 (8.5)	0.028

SAP: Stroke-associated pneumonia; APACHE II: Acute Physiology and Chronic Health Evaluation II; MDR: Multi-drug resistant; MV: Mechanical ventilation; ICU: Intensive care unit.