Glycemic indicators influence hypercoagulability via multisystem pathways in psychiatric inpatients: Structural equation modeling

Table 5 Standardized direct, indirect, and total effects of glycemic markers on D-dimer (+) across diagnostic groups (structural equation modeling)

Effect	Marker	Overall β (95%CI)	Std.β	SCZ β (95%CI)	SCZ Std.β	BD β (95%CI)	BD Std.β	MDD β (95%CI)	MDD Std.β
Direct	FPG	0.044 (0.017 to 0.071)	0.115	0.036 (-0.004 to 0.076)	0.11	0.057 (-0.007 to 0.121)	0.128	0.045 (-0.005 to 0.095)	0.094
Direct	FA	-0.640 (-0.879 to -0.402)	-0.192	-0.682 (-1.035 to -0.329)	-0.235	-0.665 (-1.257 to -0.073)	-0.172	-0.634 (-1.063 to -0.205)	-0.162
Direct	HbA1c	0.037 (-0.059 to 0.134)	0.035	0.026 (-0.126 to 0.179)	0.03	0.069 (-0.160 to 0.298)	0.059	0.085 (-0.090 to 0.259)	0.059
Indirect	FPG	-0.001 (-0.002 to -0.000)	-0.004	-0.001 (-0.002 to 0.000)	-0.003	0.000 (-0.003 to 0.003)	0	-0.001 (-0.003 to 0.002)	-0.001
Indirect	FA	-0.012 (-0.021 to -0.004)	-0.004	-0.003 (-0.010 to 0.004)	-0.001	-0.020 (-0.047 to 0.008)	-0.005	-0.019 (-0.043 to 0.005)	-0.005
Indirect	HbA1c	-0.002 (-0.004 to 0.001)	-0.002	-0.000 (-0.003 to 0.002)	0	-0.008 (-0.019 to 0.003)	-0.007	-0.016 (-0.028 to -0.003)	-0.011
Total	FPG	0.043 (0.016-0.070)	0.112	0.035 (-0.005 to 0.075)	0.107	0.056 (-0.008 to 0.121)	0.127	0.045 (-0.005 to 0.095)	0.093
Total	FA	-0.652 (-0.891 to -0.414)	-0.196	-0.685 (-1.037 to -0.332)	-0.236	-0.684 (-1.278 to -0.091)	-0.178	-0.653 (-1.081 to -0.225)	-0.167
Total	HbA1c	0.035 (-0.061 to 0.133)	0.033	0.026 (-0.126 to 0.178)	0.029	0.061 (-0.169 to 0.291)	0.052	0.069 (-0.104 to 0.242)	0.048

CI: Confidence interval; SCZ: Schizophrenia; BD: Bipolar disorder; MDD: Major depressive disorder; FPG: Fasting plasma glucose; FA: Fructosamine; HbA1c: Glycated hemoglobin.