Evolocumab intensive lipid-lowering therapy on prognosis of post-cerebral infarction depression

Figure 1 Longitudinal changes in depression severity and proprotein convertase subtilisin/kexin type 9 levels. Trajectories of 17-item Hamilton Depression Rating Scale (HAMD-17) scores (left Y-axis, solid lines) and serum proprotein convertase subtilisin/kexin type 9 levels (right Y-axis, dashed lines) over 24 weeks. Red and blue lines represent the intensive and standard groups for HAMD-17, respectively. Purple and teal lines represent proprotein convertase subtilisin/kexin type 9 levels. Gray dotted line indicates remission threshold (HAMD-17 < 7), orange dotted line indicates mild depression threshold (HAMD-17 = 14). ^cP < 0.001 for between-group differences at indicated time points. Data are presented as mean values. HAMD-17: 17-item Hamilton Depression Rating Scale; PCSK9: Proprotein convertase subtilisin/kexin type 9.