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Retrospective Study
©The Author(s) 2026.
World J Psychiatry. Jan 19, 2026; 16(1): 113104
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.113104
Table 3 Risk factors for post-stroke anxiety and depression: Multivariate analysis
Risk factor
Odds ratio
95% confidence interval
P value
Female gender2.321.56-3.45< 0.001
History of mental disorders prior to stroke3.171.89-5.32< 0.001
Infarct location in the frontal lobe or limbic system2.861.73-4.71< 0.001
Stroke severity with NIHSS ≥ 8 at admission2.541.62-3.99< 0.001
Low social support (SSRS score < 35)2.181.42-3.360.002
Smoking history1.450.92-2.290.110
Alcohol history1.320.81-2.160.265
History of hypertension1.280.85-1.930.246
History of diabetes1.540.98-2.420.062


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