Risk factors and early identification markers for post-ischemic stroke anxiety and depression

Table 2 Stroke characteristics and post-stroke anxiety and depression

Stroke characteristic	PSD group (n = 46)	Non-PSD group (n = 66)	P value
NIHSS score at admission	8.2 ± 2.3	5.1 ± 1.8	< 0.001
Stroke location
Frontal lobe infarct	32.0	17.4	0.003
Limbic system infarct (including anterior cingulate cortex and basal ganglia-thalamic regions)	28.1	15.2	0.006
Functional status at 2 weeks post-stroke
mRS score	3.1 ± 0.9	2.0 ± 0.7	< 0.001
BI score	65.0 ± 15.0	80.0 ± 10.0	< 0.001
TOAST classification			0.327
History of stroke recurrence	15.2	9.1	0.345
Time of stroke onset (hours)	4.5 ± 1.2	3.0 ± 0.8	0.023
Systolic blood pressure at stroke onset (mmHg)	160.0 ± 20.0	150.0 ± 15.0	0.047
Blood glucose level at stroke onset (mmol/L)	7.5 ± 1.5	6.8 ± 1.0	0.032

PSD: Post-stroke anxiety and depression; NIHSS: National Institutes of Health Stroke Scale; mRS: Modified Rankin Scale; BI: Barthel Index; TOAST: Trial of Org 10172 in Acute Stroke Treatment Classification.