Abnormal regional spontaneous brain activity in major depressive disorder with obesity comorbidity: A resting-state functional magnetic resonance imaging study

doi:10.5498/wjp.v16.i1.113064

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World Journal of Psychiatry

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2220-3206

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World J Psychiatry. Jan 19, 2026; 16(1): 113064
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.113064

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Figure 1 Brain regions showing differences among the healthy control, obesity, major depressive disorder, and comorbid major depressive disorder-obesity groups. A: Left middle temporal gyrus; B: Right cuneus; C: Left precuneus; D: Left thalamus. Corrected for multiple comparisons using family-wise error rate cluster-wise corrected. MDD: Major depressive disorder; HC: Healthy control; OB: Obesity; Cuneus.R: Cuneus right; Precuneus.L: Precuneus left; Thalamus.L: Thalamus left; Gyrus.L: Gyrus left. ^aP < 0.05, ^bP < 0.01, and ^cP < 0.001.

Citation: Hou XF, Mei BH, Wang X, Zhao FT, He L, Chen QY, Zang C, Wang C, Tang YF, Li XX, Zhang HF, Wang N, Cao B. Abnormal regional spontaneous brain activity in major depressive disorder with obesity comorbidity: A resting-state functional magnetic resonance imaging study. World J Psychiatry 2026; 16(1): 113064
URL: https://www.wjgnet.com/2220-3206/full/v16/i1/113064.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i1.113064

Hou XF, Mei BH, Wang X, Zhao FT, He L, Chen QY, Zang C, Wang C, Tang YF, Li XX, Zhang HF, Wang N, Cao B. Abnormal regional spontaneous brain activity in major depressive disorder with obesity comorbidity: A resting-state functional magnetic resonance imaging study. World J Psychiatry 2026; 16(1): 113064 [PMID: 41607434 DOI: 10.5498/wjp.v16.i1.113064]

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