Clinical efficacy and effects on hypothalamic-pituitary-adrenal axis function of proscar combined with selective serotonin reuptake inhibitor in post-stroke depression

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Jan 19, 2026; 16(1): 112139
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.112139

Table 4 Comparison of serum cortisol and corticotropin-releasing hormone levels before and after treatment between groups, mean ± SD

Group	Cases	Cortisol (μg/dL)		T value	P value	Corticotropin-releasing hormone (pg/mL)		T value	P value
Group	Cases	Pre-treatment	Post-treatment	T value	P value	Pre-treatment	Post-treatment	T value	P value
Control	46	11.42 ± 1.44	8.23 ± 1.05	12.140	0.000	305.38 ± 21.42	257.66 ± 18.29	11.491	0.000
Study	46	11.51 ± 1.37	6.84 ± 1.12	17.899	0.001	306.03 ± 22.26	198.28 ± 14.49	27.514	0.000
T value		0.307	6.141			0.143	17.259
P value		0.759	0.001			0.887	0.001

Citation: Xu MY, Lu Y, Shi GM, Yao J, Ding CQ, Zhou RJ. Clinical efficacy and effects on hypothalamic-pituitary-adrenal axis function of proscar combined with selective serotonin reuptake inhibitor in post-stroke depression. World J Psychiatry 2026; 16(1): 112139
URL: https://www.wjgnet.com/2220-3206/full/v16/i1/112139.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i1.112139

Xu MY, Lu Y, Shi GM, Yao J, Ding CQ, Zhou RJ. Clinical efficacy and effects on hypothalamic-pituitary-adrenal axis function of proscar combined with selective serotonin reuptake inhibitor in post-stroke depression. World J Psychiatry 2026; 16(1): 112139 [PMID: 41555951 DOI: 10.5498/wjp.v16.i1.112139]

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