Correlation of ocular surface function with sleep quality, anxiety, and depression in patients with dry eye disease

Table 5 Correlation among the ocular surface status indicators, sleep quality, anxiety, and depression

Variable		PSQI	SAS	SDS	OSDI	TBUT	FL	SIT
PSQI	r	1	0.1574	0.207	0.245	-0.177	0.206	-0.116
	P value		0.003	< 0.001	< 0.001	< 0.001	< 0.001	0.028
SAS	r	0.1574	1	0.162	0.183	-0.208	0.218	-0.167
	P value	0.003		0.002	< 0.001	< 0.001	< 0.001	0.001
SDS	r	0.207	0.162	1	0.200	-0.162	0.284	-0.234
	P value	< 0.001	0.002		< 0.001	0.002	< 0.001	< 0.001
OSDI	r	0.245	0.183	0.200	1	-0.111	0.213	-0.245
	P value	< 0.001	< 0.001	< 0.001		0.037	< 0.001	< 0.001
TBUT	r	-0.177	-0.208	-0.162	-0.111	1	-0.254	0.195
	P value	< 0.001	< 0.001	0.002	0.037		< 0.001	< 0.001
FL	r	0.206	0.218	0.284	0.213	-0.254	1	-0.280
	P value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001		< 0.001
SIT	r	-0.116	-0.167	-0.234	-0.245	0.195	-0.280
	P value	0.028	0.001	< 0.001	< 0.001	< 0.001	< 0.001

PSQI: Pittsburgh Sleep Quality Index; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale; OSDI: Ocular surface disease index; TBUT: Tear film break-up time; FL: Fluorescein staining score; SIT: Schirmer I test.