Effects of celecoxib combined with duloxetine on chronic pain, depression, and anxiety in patients with knee osteoarthritis

Table 4 Changes in anxiety and depression scores

Group	SAS		SDS
	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment
Control group (n = 57)	64.98 ± 4.69	46.58 ± 5.11a	67.00 (63.00, 70.00)	48.26 ± 5.26a
Study group (n = 66)	64.16 ± 4.94	52.56 ± 5.86a	66.00 (64.00, 71.00)	52.46 ± 3.35a
t value	0.948	-5.988	0.573	-5.347
P value	0.345	< 0.001	0.567	< 0.001

^aP < 0.05 vs pre-treatment score.

SAS: Self-rating Anxiety Scales; SDS: Self-rating Depression Scales.