Disease duration-stratified associations of thyroid hormone levels with psychopathology in hospitalized patients with schizophrenia: A cross-sectional study

Table 1 General information of enrolled in patients with stable schizophrenia, n (%)

General information		Total participants (n = 237)
Age (years), median (IQR)		50 (40-56)
Male sex		138 (58.2)
BMI (kg/m²), median (IQR)		24.49 (21.88-27.53)
Marital status (married)		49 (20.7)
Education attainment	Illiterate	15 (6.3)
	High school and below	201 (84.8)
	University and above	21 (8.9)
Age at onset(years), median (IQR)		26 (20-35)
Disease duration (years), median (IQR)		30 (24-34)
Hospitalization duration (months), median (IQR)		26 (8-51.5)
Family psychiatric history (yes)		54 (22.8)
First episode (yes)		4 (1.7)
Substance use history (yes)	Smoking	97 (40.9)
	Alcohol use	59 (24.9)
Antipsychotics type	Typical	4 (1.7)
	Atypical	216 (91.1)
	Combined	17 (7.2)
Chlorpromazine equivalent dose (mg/day), median (IQR)		325 (200-550)
Chronic diseases (≥ 1)		79 (33.3)
Vision impairment		32 (13.5)
Hearing impairment		16 (6.8)
Falls history (yes)		15 (6.3)
COVID-19 infection history (yes)		94 (39.7)
PHQ-9 (depression), median (IQR)		3 (1-5)
GAD-7 (anxiety), median (IQR)		1 (0-3)
MoCA-C (cognitive function), median (IQR)		18 (11.5-23)
PANSS profile-total score, median (IQR)		61 (51-72)
PANSS profile-positive symptoms, median (IQR)		13 (9-17)
PANSS profile-negative symptoms, median (IQR)		18 (14-23)
PANSS profile-general psychopathology, median (IQR)		29 (25-35)
TSH (μIU/mL), median (IQR)		2.36 (1.78-3.47)
FT3 (pmol/L), median (IQR)		4.89 (4.44-5.27)
FT4 (pmol/L), median (IQR)		15.73 (14.14-17.68)
T3 (ng/mL), median (IQR)		1.08 (0.97-1.22)
T4 (μg/dL), median (IQR)		7.8 (6.91-8.8)

BMI: Body mass index; COVID-19: Coronavirus disease 2019; IQR: Interquartile range; PHQ-9: Patient Health Questionnaire-9; GAD-7: Generalized Anxiety Disorder 7-item; MoCA-C: Montreal Cognitive Assessment-Chinese version; PANSS: Positive and Negative Syndrome Scale; TSH: Thyroid stimulating hormone; T3: Triiodothyronine; FT3: Free triiodothyronine; T4: Thyroxine; FT4: Free thyroxine.