Community-based assisted screening for mild cognitive impairment using gait and handwriting kinematic parameters analysis

doi:10.5498/wjp.v15.i9.109478

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Clinical Trial

World J Psychiatry. Sep 19, 2025; 15(9): 109478
Published online Sep 19, 2025. doi: 10.5498/wjp.v15.i9.109478

Table 3 Comparison of graphic tasks kinematic parameters between groups, M (QR)

Parameters	Handwriting with graphic tasks
Parameters	MCI group (n = 34)	CN group (n = 61)	t/Z	P value
Tilt angle	-42.07 (22.51)	-39.79 (19.18)	-0.823	0.411
Average pressure	593.05 (258.14)	666.84 (172.65)	-2.135	0.033
Time in air	25920.00 (18039.00)	17468.00 (11452.00)	-2.865	0.004
Single stroke time	1526.07 (1304.64)	1605.43 (1058.23)	-0.116	0.907
Single stroke length	13.23 (7.44)	14.84 (7.15)	-1.623	0.105
X-axis stroke length	8.22 (4.41)	9.34 (4.69)	-1.669	0.095
Y-axis stroke length	8.32 (4.63)	9.61 (5.13)	-1.304	0.192
Total single stroke length	255.93 (71.32)	260.29 (77.99)	-0.155	0.877
Total X-axis stroke length, mean (SD)	167.93 ± 36.92	168.48 ± 35.30	0.072	0.943
Total Y-axis stroke length	157.47 (50.29)	157.95 (47.77)	-0.738	0.461
Average velocity	10.40 (4.93)	11.12 (5.53)	-1.623	0.105
Average velocity in X-axis	6.91 (2.92)	8.12 (3.46)	-1.933	0.053
Average velocity in Y-axis	7.59 (3.34)	7.71 (3.57)	-1.102	0.270
Maximum velocity in X-axis	29.07 (9.53)	36.22 (16.09)	-3.237	0.001
Minimum velocity in X-axis	0.14 (0.32)	0.08 (0.25)	-0.927	0.354
Maximum velocity in Y-axis	33.27 (16.84)	38.45 (17.21)	-1.723	0.085
Minimum velocity in Y-axis	0.13 (0.26)	0.11 (0.25)	-0.617	0.537
Number of times velocity slows down	26.33 (22.87)	28.95 (23.08)	-0.078	0.938
Average acceleration in X-axis	0.21 (0.07)	0.25 (0.09)	-2.880	0.004
Average acceleration in Y-axis	0.23 (0.11)	0.26 (0.08)	-1.987	0.047
Maximum acceleration in X-axis	1.07 (0.32)	1.38 (0.55)	-3.998	< 0.001
Minimum acceleration in X-axis	0.00 (0.01)	0.00 (0.01)	-0.163	0.870
Maximum acceleration in Y-axis	1.27 (0.64)	1.45 (0.65)	-2.050	0.040
Minimum acceleration in Y-axis	0.00 (0.01)	0.00 (0.01)	-0.513	0.608
Number of times acceleration slows down	26.19 (24.49)	30.21 (24.99)	-0.039	0.969
Task score	5.00 (3.00)	6.00 (2.00)	-2.447	0.014

MCI: Mild cognitive impairment; CN: Cognitively normal.

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Citation: Ren YX, Wu B, Lou JL, Zhu XR, Zhang C, Lang Q, Wei ZQ, Su LM, Qi HN, Wang LN. Community-based assisted screening for mild cognitive impairment using gait and handwriting kinematic parameters analysis. World J Psychiatry 2025; 15(9): 109478
URL: https://www.wjgnet.com/2220-3206/full/v15/i9/109478.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i9.109478

Ren YX, Wu B, Lou JL, Zhu XR, Zhang C, Lang Q, Wei ZQ, Su LM, Qi HN, Wang LN. Community-based assisted screening for mild cognitive impairment using gait and handwriting kinematic parameters analysis. World J Psychiatry 2025; 15(9): 109478 [PMID: 40933146 DOI: 10.5498/wjp.v15.i9.109478]

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