Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression

doi:10.5498/wjp.v15.i9.109458

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Sep 19, 2025; 15(9): 109458
Published online Sep 19, 2025. doi: 10.5498/wjp.v15.i9.109458

Table 6 Comparison of long-term efficacy statistics between two groups of patients

	n	BRANS	MCCB	HAMD-24	WCST	TOH
Combined group	55	1.49 ± 0.49	1.16 ± 0.44	-0.54 ± 0.37	0.07 ± 0.02	1.28 ± 0.65
Control group	54	1.44 ± 0.52	1.12 ± 0.47	-0.52 ± 0.41	0.06 ± 0.02	1.25 ± 0.59
t value		0.182	0.106	0.124	0.085	0.127
P value		0.874	0.926	0.908	0.956	0.905

BRANS: Battery for the Assessment of Neuropsychological Status score; MCCB: Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery; HAMD-24: Hamilton Depression Scale-24; WCST: Wisconsin Card Sorting Test; TOH: Tower of Hanoi.

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Citation: Zhao GG, Zhao J, Kong Y, Pang YP, Zheng XN, Zhang YW. Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression. World J Psychiatry 2025; 15(9): 109458
URL: https://www.wjgnet.com/2220-3206/full/v15/i9/109458.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i9.109458

Zhao GG, Zhao J, Kong Y, Pang YP, Zheng XN, Zhang YW. Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression. World J Psychiatry 2025; 15(9): 109458 [PMID: 40933153 DOI: 10.5498/wjp.v15.i9.109458]

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