Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression

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Sep 19, 2025 (publication date) through Aug 30, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Sep 19, 2025; 15(9): 109458
Published online Sep 19, 2025. doi: 10.5498/wjp.v15.i9.109458

Table 2 Comparison of electroconvulsive therapy monitoring indicators between combination group and control group

	n	Initial threshold charge (mc)	Final threshold charge (mc)	Total treatment electricity (mc)	Mean seizure duration (mc)
Combined group	56	116.02 ± 13.76	144.01 ± 13.73	1266.07 ± 212.01	50.06 ± 8.08
Control group	54	114.18 ± 14.56	170.23 ± 24.76	1866.02 ± 260.82	48.77 ± 8.82
t value		2.007	-52.149	-99.285	2.016
P value		0.475	0.000	0.000	0.478

Citation: Zhao GG, Zhao J, Kong Y, Pang YP, Zheng XN, Zhang YW. Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression. World J Psychiatry 2025; 15(9): 109458
URL: https://www.wjgnet.com/2220-3206/full/v15/i9/109458.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i9.109458