Anxiety and depression in recurrent implantation failure after frozen-thawed embryo transfer and efficacy of endometrial receptivity testing

Table 2 Univariate analysis of factors associated with anxiety and depression in patients with recurrent implantation failure

Characteristics	Anxiety group (n = 204)	Non-anxiety group (n = 167)	χ2/t	P value	Depression group (n = 227)	Non-depression group (n = 144)	χ2/t	P value
Age (years)	-	-	9.655	0.002	-	-	13.001	0.000
≤ 35	83	95	-	-	92	86	-	-
> 35	121	72	-	-	135	58	-	-
BMI (kg/m2)	22.08 ± 2.09	21.82 ± 2.28	1.149	0.251	21.91 ± 2.04	22.04 ± 2.38	0.581	0.562
Marital status	-	-	5.171	0.023	-	-	0.253	0.615
First marriage	103	104	-	-	129	78	-	-
Remarriage	101	63	-	-	98	66	-	-
Educational attainment	-	-	0.402	0.526	-	-	2.160	0.023
Senior high school/technical secondary school or below	91	80	-	-	94	77	-	-
College/bachelor's degree or above	113	87	-	-	133	67	-	-
Annual household income (in ten thousand yuan)	-	-	9.931	0.007	-	-	21.832	< 0.0001
< 5	49	19	-	-	53	15	-	-
5-10	88	87	-	-	115	60	-	-
> 10	67	61	-	-	59	69	-	-
Occupation	-	-	1.117	0.773	-	-	5.219	0.157
Work unit	51	38	-	-	48	41	-	-
Self-employed	46	42	-	-	62	26	-	-
Farmer	54	49	-	-	62	41	-	-
Unemployed	53	38	-	-	55	36	-	-
Residential area	-	-	1.922	0.166	-	-	7.038	0.008
Urban	115	106	-	-	123	98	-	-
Rural	89	61	-	-	104	46	-	-
Type of infertility	-	-	0.703	0.402	-	-	0.167	0.683
Primary	84	76	-	-	96	64	-	-
Secondary	120	91	-	-	131	80	-	-
Infertility duration (years)	-	-	13.012	0.002	-	-	9.426	0.009
< 3	51	58	-	-	50	60	-	-
3-5	81	59	-	-	86	54	-	-
> 5	72	50	-	-	91	30	-	-
Cause of infertility	-	-	9.871	0.020	-	-	9.896	0.019
Male-factor	51	57	-	-	70	38	-	-
Female-factor	86	45	-	-	76	55	-	-
Combined male-female-factor	31	33	-	-	31	33	-	-
Unexplained	36	32	-	-	50	18	-	-
Female party’s only-child status	-	-	1.100	0.294	-	-	0.056	0.813
Yes	83	77	-	-	99	61	-	-
No	121	90	-	-	128	83	-	-
Spouse’s only-child status	-	-	5.602	0.018	-	-	2.036	0.154
Yes	124	71	-	-	126	69	-	-
No	80	96	-	-	101	75	-	-
Infertility treatment duration (years)	-	-	17.033	0.001	-	-	7.202	0.066
< 1	68	57	-	-	78	47	-	-
1-3	40	60	-	-	62	38	-	-
3-5	37	24	-	-	44	17	-	-
> 5	59	26	-	-	43	42	-	-
Number of failed implantation attempts	-	-	12.301	0.001	-	-	18.081	< 0.0001
2	91	105	-	-	100	96	-	-
≥ 3	113	62	-	-	127	48	-	-

BMI: Body mass index.