Depressive state on cardiac remodeling and left ventricular function in chronic heart failure: A retrospective study

Table 8 Multivariate analysis and risk assessment

Factor	Adjusted risk ratio	95% confidence interval	P value
Depression	1.76	1.45-2.12	< 0.001
Inflammatory response activation	1.52	1.23-1.88	< 0.001
Neuroendocrine regulation abnormalities	1.65	1.37-2.00	< 0.001
Increased oxidative stress	1.48	1.20-1.83	< 0.001
Disrupted cell apoptosis programs	1.70	1.40-2.05	< 0.001
Autonomic nervous system imbalance	1.60	1.32-1.93	< 0.001
Poor sleep quality	1.45	1.18-1.78	< 0.001
Inflammatory response activation	1.52	1.23-1.88	< 0.001
Low social support	1.55	1.27-1.89	< 0.001