Depressive state on cardiac remodeling and left ventricular function in chronic heart failure: A retrospective study

Table 3 Myocardial fibrosis and inflammatory response

Indicator	Depressed group (n = 124)	Non-depressed group (n = 124)	P value
Myocardial fibrosis area (%)	15.6 ± 3.4	8.7 ± 2.6	< 0.01
High-sensitivity C-reactive protein (mg/L)	8.7 ± 2.3	4.5 ± 1.6	< 0.01
Tumor necrosis factor-α (pg/mL)	42.5 ± 7.6	28.3 ± 5.4	< 0.01
Neutrophil-to-lymphocyte ratio	3.2 ± 0.8	2.1 ± 0.6	< 0.01
Systemic immune-inflammation index	950 ± 150	750 ± 120	< 0.01
Systemic inflammatory response index	1.8 ± 0.4	1.2 ± 0.3	< 0.01
Inflammatory prognostic index	2.5 ± 0.6	1.5 ± 0.4	< 0.01
Transforming growth factor-β1 (ng/mL)	12.4 ± 2.3	8.9 ± 1.8	< 0.01
Interleukin-6 (pg/mL)	34.2 ± 5.8	22.1 ± 4.7	< 0.01