Copyright
©The Author(s) 2025.
World J Psychiatry. Aug 19, 2025; 15(8): 106303
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.106303
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.106303
Table 1 Sociodemographic and clinical characteristics of healthy controls and patients with depression, n (%)
| Characteristics | HC (n = 279) | MD (n = 164) | Statistics | P value |
| Age (year), mean ± SD | 44.1 ± 8.0 | 44.6 ± 6.7 | -1.130 | 0.258 |
| Gender | ||||
| Male | 98 (35.1) | 59 (36.0) | 0.033 | 0.857 |
| Female | 181 (64.9) | 105 (64.0) | - | - |
| Smoking | ||||
| No | 7 (2.5) | 23 (14.0) | 21.694 | < 0.001 |
| Yes | 272 (97.5) | 141 (86.0) | - | - |
| SBP (mmHg), mean ± SD | 105.3 ± 13.9 | 122.0 ± 17.7 | -9.974 | < 0.001 |
| DBP (mmHg), mean ± SD | 72.2 ± 8.3 | 79.2 ± 11.0 | -7.036 | < 0.001 |
| Hypertension | ||||
| Yes | 10 (3.6) | 30 (18.3) | 27.203 | < 0.001 |
| No | 269 (96.4) | 134 (81.7) | - | - |
| Diabetes | ||||
| Yes | 3 (1.1) | 9 (5.5) | 7.751 | 0.005 |
| No | 276 (98.9) | 155 (94.5) | - | - |
| Illness duration, month, mean ± SD | - | 68.8 ± 75.5 | - | - |
| Medication duration, month, mean ± SD | - | 44.8 ± 57.2 | - | - |
| Attack times, mean ± SD | - | 1.9 ± 1.1 | - | - |
| Family history of depression | - | - | - | - |
| Yes | - | - | - | - |
| No | - | - | - | - |
| FRS (%), mean ± SD | 2.3 (2.1) | 5.3 ± 5.3 | -8.538 | < 0.001 |
- Citation: Zhou LN, Mao Y, Li BJ, Ma XC, Wang W. Novel biomarkers of the Framingham risk score in patients with depression: A cross-sectional study. World J Psychiatry 2025; 15(8): 106303
- URL: https://www.wjgnet.com/2220-3206/full/v15/i8/106303.htm
- DOI: https://dx.doi.org/10.5498/wjp.v15.i8.106303