Expression differences and relationships of endothelin-1, interleukin-6 and c-kit in hypertensive patients with and without depression

Table 4 Diagnostic value of endothelin-1, interleukin-6, stem cell factor c-kit, and their combination for hypertension with depression

Indicator	Optimal cutoff value	AUC	95%CI	P value	Sensitivity (%)	Specificity (%)
ET-1	165.73 ng/L	0.746	0.675-0.832	< 0.05	72.56	75.38
IL-6	96.04 ng/L	0.801	0.743-0.889	< 0.05	75.43	67.62
SCF	847.36 ng/L	0.732	0.654-0.817	< 0.05	70.85	74.19
c-kit	11.53 μg/L	0.779	0.707-0.876	< 0.05	77.62	70.57
Combined	-	0.884	0.813-0.957	< 0.05	90.24	85.37

ET-1: Endothelin-1; IL-6: Interleukin-6; SCF: Stem cell factor; AUC: Area under the curve.