Clinical manifestations of anxiety and depression in sepsis-associated encephalopathy and multi-omics identification of cluster of differentiation 38 as an early biomarker

Table 4 Comparison of depression symptoms between the sepsis and sepsis-associated encephalopathy groups (Hamilton Depression Rating Scale), mean ± SD

	Sepsis-no encephalopathy (n = 29)	Sepsis-associated encephalopathy (n = 29)	P value
Depression symptoms score (HAM-D)	9.1 ± 2.3	16.0 ± 3.5	0.003
Low mood	2.1 ± 1.0	4.5 ± 1.2	0.004
Loss of interest	1.8 ± 0.9	3.9 ± 1.1	0.008
Insomnia	1.2 ± 0.6	2.6 ± 0.9	0.019
Low self-esteem	1.0 ± 0.5	2.0 ± 0.8	0.028

HAM-D: Hamilton depression rating scale.