Copyright
©The Author(s) 2025.
World J Psychiatry. Jun 19, 2025; 15(6): 104809
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.104809
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.104809
Figure 7 Supplementation with Lactobacillus complex alleviates anxiety and depression-like behavior in one day of hypobaric hypoxia exposure mice.
A: Schematic diagram of oral supplementation with Lactobacillus complex in mice; B: Lactobacillus supplementation experiment paradigm; C: Total distance for each group in the open field test (n = 8); D: Central distance for each group in the open field test (n = 8); E: Entries to the central zone for each group in the open field test (n = 8); F: Time spend in the open arm for each group in the elevated plus maze test (n = 8); G: Entries to the open arm for each group in the elevated plus maze test (n = 8); H: Time spend in the close arm for each group in the elevated plus maze test (n = 8); I: Immobility latency for each group in the forced swim test (n = 8); J: Immobility time or each group in the forced swim test (n = 8); K: Cluster heat-map for open field test across groups; L: Cluster heat-map for elevated plus maze across groups. NS: No significance; Con: Control group; HH1: One day of hypobaric hypoxia exposure; HH: Hypobaric hypoxia; OFT: Open field test; EPM: Elevated plus maze; FST: Forced swim test.
- Citation: Chang WY, Qin QZ, Li XT, Wang JJ, Chen Y, Ruan HQ, Qu YN, Jiang XX, He HX. Modulating oral microbiota ameliorates hypobaric hypoxia-induced anxiety- and depression-like behaviors in mice. World J Psychiatry 2025; 15(6): 104809
- URL: https://www.wjgnet.com/2220-3206/full/v15/i6/104809.htm
- DOI: https://dx.doi.org/10.5498/wjp.v15.i6.104809