Diagnostic dynamic contrast-enhanced magnetic resonance imaging blood-brain barrier assessment combined with plasma biomarkers for mild cognitive impairment

doi:10.5498/wjp.v15.i6.103661

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Jun 19, 2025; 15(6): 103661
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.103661

Table 2 Comparison of various scale scores among three groups, mean ± SD

	Control group (n = 55)	na-MCI group (n = 50)	a-MCI group (n = 52)	F value	P value
MoCA	28.05 ± 0.85	21.86 ± 2.05^a^,¹	21.23 ± 2.13^a^,¹	247.0	< 0.0001
AVLT-H-N5	6.16 ± 1.44	2.24 ± 0.69^a^,¹	2.31 ± 0.58^a^,¹	275.8	< 0.0001
HAMA	3.31 ± 2.10	5.16 ± 1.02^a^,¹	7.06 ± 1.00^a^,¹^,²	85.25	< 0.0001
HAMD	1.95 ± 0.23	6.00 ± 0.64^a^,¹	7.15 ± 0.61^a^,¹^,²	1488	< 0.0001
ADL	23.09 ± 1.17	26.24 ± 1.55^a^,¹	28.58 ± 1.21^a^,¹^,²	234.9	< 0.0001

^aP < 0.05.

¹P vs control group.

²P vs non-amnestic mild cognitive impairment group.

MoCA: Montreal cognitive assessment; AVLT-H-N5: Auditory verbal learning test-Huashan version delayed recall score (N5 dimension); HAMA: Hamilton anxiety scale; HAMD: Hamilton depression scale; ADL: Activity of daily living; a-MCI: Amnestic mild cognitive impairment; na-MCI: Non-amnestic mild cognitive impairment.

Citation: Sun L, Xu MR, Zhou CY, Cao SD, Zhang XL, Guan SQ, Sang WX, Li XL. Diagnostic dynamic contrast-enhanced magnetic resonance imaging blood-brain barrier assessment combined with plasma biomarkers for mild cognitive impairment. World J Psychiatry 2025; 15(6): 103661
URL: https://www.wjgnet.com/2220-3206/full/v15/i6/103661.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i6.103661