Factors influencing anxiety and depression in advanced hepatocellular carcinoma patients and their impact on quality of life

Table 3 Binary logistic regression analysis of hepatocellular carcinoma combined with depression

Variable	OR	95%CI	P value
Education (primary & secondary vs senior high school)	1.693	1.124-2.538	0.028
Live alone (yes vs no)	1.163	0.718-1.544	0.951
KPS score (> 80 vs 60-80)	0.856	0.573-0.969	0.012
HAMA score (≥ 14 vs < 14)	2.003	1.539-2.651	< 0.001
HAMD score (> 8 vs ≤ 8)	1.826	1.324-2.318	< 0.001
Previous liver resection (yes vs no)	1.267	1.152-1.634	0.017
TACE/HAIC (yes vs no)	1.318	1.167-1.826	< 0.001
BCLC stage (C vs B)	1.423	1.175-1.953	< 0.001
Number of tumors (multiple vs single)	2.528	1.582-3.256	0.034
FACT-Hep scores (good vs poor)	0.643	0.458-0.985	< 0.001
Social support (high vs low & moderate)	0.722	0.603-0.987	< 0.001

OR: Odds ratio; CI: Confidence interval; KPS: Karnofsky performance score; HAMA: Hamilton Anxiety Rating Scale; HAMD: Hamilton Depression Rating Scale; TACE: Transcatheter arterial chemoembolization; HAIC: Hepatic artery infusion chemotherapy; BCLC: Barcelona Clinic Liver Cancer; FACT-Hep: Functional Assessment of Cancer Therapy-Hepatobiliary Questionnaire.